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7:30 AM–8:15 AM FINANCE COMMITTEE MEETING—Spyglass 2
7:00 AM–8:00 AM BDRB EDITORIAL BOARD MEETING—Cypress 3
8:00 AM–7:00 PM REGISTRATION—Regency Foyer
8:00 AM–8:30 AM COFFEE AND CONTINENTAL BREAKFAST—Regency Foyer
8:30 AM–8:45 AM PRESIDENT’S WELCOME—Regency Main Ballroom
8:45 AM–9:45 AM JOSEF WARKANY LECTURE—Regency Main Ballroom
Speaker: Richard H. Finnell, Institute of Biosciences and Teratology, Texas A&M Health Science Center
9:45 AM–10:00 AM BREAK
10:00 AM–12:30 PM STUDENT/POSTDOCTORAL FELLOW PLATFORM SESSION I—Regency Main Ballroom
Organized by the Student Affairs Committee
Chairpersons: Mary Alice Smith, University of Georgia and Michael D. Collins, UCLA School of Public Health
10:00 AM–10:15 AM Introduction
10:15 AM–10:30 AM 1 Is GAPDH a Sensitive Target for the Teratogen-Induced Oxidative Stress That Occurs Selectively in the Caudal Region of Organogenesis Stage Embryos?
Yan J, Hales BF. McGill University, Montreal, QC, Canada.
10:30 AM–10:45 AM 2 Prenatal Origins of Hypertension Induced by Gestational Undernutrition or Environmental Chemical Exposure
Ellis-Hutchings RG, Zucker RM, Lau CS, Grey BE, Rogers JM. Reproductive Toxicology Division, NHEERL, ORD, US EPA, Research Triangle Park, NC, United States.
10:45 AM–11:00 AM 3 Examination of Dose and Time Dependent Arsenic and Cadmiuminduced Gene Expression Response in C57BL/6 Mouse Embryos Undergoing Neurulation
Robinson JF, Yu X, Hong S, Faustman EM. University of Washington, Seattle, WA, United States.
11:00 AM–11:15 AM 4 Glyceryl Trinitrate (GNT): A Model Compound for Investigating the Mechanism of Nitro Based Developmental Toxicity
Bardai GK1,2, Hales BF2, Sunahara GI1. 1National Research Council of Canada, Montreal, QC, Canada, 2McGill University, Montreal, QC, Canada.
11:15 AM–11:30 AM 5 Gestational High Saturated Fat Diet Alters C57BL/6 Mouse Skeletal Formation
Liang C1, Oest ME1, Jones JC1, Prater MR2. 1Virginia Polytechnic Institute and State University, Blacksburg, VA, United States, 2The Edward Via Virginia College of Osteopathic Medicine, Blacksburg, VA, United States.
11:30 AM–11:45 AM 6 Gene and miRNA Expression Differences in p53-Deficient Day-9 Mouse Embryos
Hosako H1, Martin GS1, Barrier M2, Mirkes PE1. 1Texas A&M University, College Station, TX, United States, 2U.S. Environmental Protection Agency, Research Triangle Park, NC, United States.
11:45 AM–12:00 Noon 7 Maternal and Fetal Tissue Infectivity Following an Oral Challenge With Listeria monocytogenes and an Anti-internalin Peptide in Pregnant Guinea Pigs
Williams D1, Irvin EA1, Puckett AM2, Raybourne RB4, Smith MA1,3. 1Environmental Health Science Department, University of Georgia, Athens, GA, United States, 2College of Veterinary Medicine, University of Georgia, Athens, GA, United States, 3Center for Food Safety, University of Georgia, Athens, GA, United States, 4Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, Laurel, MD, United States.
12:00 Noon–12:15 PM 8 Localized Application of Growth Differentiation Factor-10 (Gdf10) Alters Morphogenesis of the Developing Limb Bud In Vitro
Galdones E, Hales BF. Department of Pharmacology and Therapeutics, McGill University, Montreal, QC, Canada.
12:15 PM–12:30 PM 9 Genetic Susceptibility to PCB-Induced Developmental Neurotoxicity
Curran CP1,2, Williams MT3, Vorhees CV3, Patel KV2, Nebert DW2. 1CDC-NIOSH, Cincinnati, OH, United States, 2University of Cincinnati, Cincinnati, OH, United States, 3Cincinnati Children’s Research Foundation, Cincinnati, OH, United States.
12:30 PM–1:00 PM F. CLARKE FRASER AWARD—Regency Main Ballroom
If I Knew What I was Doing It Wouldn’t Be Called Research
Speaker: Terence R. S. Ozolins, Pfizer, Inc.
1:00 PM–2:00 PM LUNCH ON OWN
1:00 PM–2:00 PM EDUCATION COMMITTEE MEETING—Spyglass 2
2:00 PM–2:30 PM JAMES G. WILSON PUBLICATION AWARD—Regency Main Ballroom
2:30 PM–6:00 PM MARCH OF DIMES SYMPOSIUM—Regency Main Ballroom
Embryonic and Fetal Hypoxia
Chairpersons: Michael D. Collins, UCLA School of Public Health and
William S. Webster, University of Sydney
2:30 PM–2:35 PM Introduction
2:35 PM–3:05 PM S1 Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor-1
Speaker: Gregg L. Semenza, The Johns Hopkins University School of Medicine
3:05 PM–3:35 PM S2 The Role of Oxygen Availability in Embryonic Development and Stem Cell Function
Speaker: M. Celeste Simon, University of Pennsylvania Cancer Center
3:35 PM–4:05 PM S3 The Role of HIF in Mesenchyme Differentiation and Limb Development
Speaker: Amato Giaccia, Stanford University School of Medicine
4:05 PM–4:20 PM Break
4:20 PM–4:50 PM S4 Alpha Thalassemia and Limb Defects in Humans: A Possible Hypoxic Mechanism
Speaker: Margaret Adam, Emory University
4:50 PM–5:20 PM S5 Hypoxia as a Cause of Birth Defects
Speaker: William S. Webster, University of Sydney
5:20 PM–5:50 PM S6 Pharmacologically Induced Hypoxia: A Common Tratogenic Mechanism for Drugs with Potential to Cause Embryonic Cardiac Arrhythmia
Speaker: Bengt Danielsson, Swedish Medical Product Agency
5:50 PM–6:00 PM General Discussion
6:00 PM–7:30 PM WELCOME RECEPTION AND EXHIBITS OPEN—Monterey Grand
Ballroom
(Located in the main building near the hotel’s front desk)
7:30 PM–9:00 PM BDRA EDITORIAL BOARD MEETING—Spyglass 1
Rev. Friday, April 18, 2008; at 4:24:18 PM EST
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