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6:30 AM–7:00 AM SUNRISE MINI-COURSE BREAKFAST—Regency Main Ballroom
7:00 AM–8:30 AM SUNRISE MINI-COURSE (Separate registration required)—Regency Main Ballroom
Nanoparticles
Organized by the Education Committee: Eias A. Zahalka, Chairperson
7:00 AM–7:30 AM General Overview of Nanomaterials: What They Are, How They Are Made, and What They Are Used For
Speaker: Amy K. Madl, University of California, Davis
7:30 AM–8:00 AM Environmental Distribution (Current and Potential), Routes of Exposure, and Deposition in the Lung
Speaker: Kent E. Pinkerton, University of California, Davis
8:00 AM–8:30 AM Nanoparticles and Developmental/ Placental Toxicology
Speaker: Richard K. Miller, University of Rochester Medical Center
7:00 AM–5:00 PM REGISTRATION—Regency Foyer
8:00 AM–8:30 AM COFFEE AND CONTINENTAL BREAKFAST—Monterey Grand Ballroom
8:30 AM–9:15 AM PARTNERSHIP LECTURE—Regency Main Ballroom
Signals from Above: The Normative Interactions of Embryos and the Environment (L2)
Speaker: Scott F. Gilbert, Swarthmore College
9:15 AM–11:45 AM TS/OTIS JOINT SYMPOSIUM—Regency 1
Identifying Risk Factors for Birth Defects: An Update on the National Birth Defects Prevention Study (NBDPS)
Chairpersons: Sonja A. Rasmussen, Centers for Disease Control and Prevention and Dee L. Quinn, University of Arizona
9:15 AM–9:20 AM Introduction
Speaker: Sonja A. Rasmussen, Centers for Disease Control and Prevention
9:20 AM–9:40 AM S16 The National Birth Defects Prevention Study (NBDPS): Working Together Since 1997 to Identify Risk Factors for Birth Defects
Speaker: Jennita Reefhuis, Centers for Disease Control and Prevention
9:40 AM–10:00 AM S17 Nutrition and Birth Defects—Perspectives from the NBDPS
Speaker: Gary M. Shaw, Children’s Hospital Oakland Research Institute
10:00 AM–10:15 AM Break
10:15 AM–10:35 AM S18 Medications and Birth Defects in the NBDPS
Speaker: Allen A. Mitchell, Slone Epidemiology Center at Boston University
10:35 AM–10:55 AM S19 Incorporating Study of Genetic Risk Factors into NBDPS
Speaker: Andrew F. Olshan, University of North Carolina
10:55 AM–11:15 AM S20 Met and Unmet Health Care Needs of Children with Orofacial Clefts Enrolled in the National Birth Defects Prevention Study
Speaker: James M. Robbins, Arkansas Children’s Hospital
11:15 AM–11:35 AM S21 Large Multi-Site Epidemiologic Studies: Challenges and Opportunities
Speaker: Margaret Honein, Centers for Disease Control and Prevention
11:35 AM–11:45 AM Panel Discussion
9:15 AM–11:45 AM MARTA/MTA SYMPOSIUM—Regency Main Ballroom
Current Methods for Developmental Toxicity Screening
Chairpersons: Eve Mylchreest, Wyeth Research and Anthony M. DeLise, Sanofi-Aventis
9:15 AM–9:25 AM Introduction
Speaker: Eve Mylchreest, Wyeth Research
9:25 AM–10:00 AM S22 Embryonic Stem Cell-Based Models for Developmental Toxicology
Speaker: Donald B. Stedman, Pfizer Global Research & Development
10:00 AM–10:15 AM Break
10:15 AM–10:45 AM S23 Use of the Zebrafish Assay with Pharmaceutical Compounds
Speaker: Kimberly Brannen, Bristol-Myers Squibb
10:45 AM–11:15 AM S24 Use of Whole Embryo Culture in Pharmaceutical Screening/Testing
Speaker: Terence R.S. Ozolins, Pfizer, Inc.
11:15 AM–11:45 AM S25 Whole Embryo Culture: Novel Endpoints?
Speaker: Barbara Hales, McGill University
11:45 AM–1:30 PM TS/NBTS JOINT POSTER SESSIONS AND EXHIBITS OPEN —Monterey Grand Ballroom
Society for Birth Defects Research and Prevention Posters: P45–P74
NBTS Posters: NBTS 31–NBTS 40
12:30 PM–1:30 PM 2009 PROGRAM COMMITTEE MEETING—Spyglass 2
1:30 PM–3:15 PM JOINT TS/NBTS PLATFORM SESSION IV—Regency 4
CNS and Prenatal Exposures: Teratological and Neurodevelopmental Outcomes
Chairpersons: Jane Adams, University of Massachusetts and Charles V. Vorhees, Cincinnati Children’s Research Foundation
1:30 PM–1:45 PM 29 Incidence of Major Malformations in Infants Following Antidepressant Exposure in Pregnancy: Results of a Large Cohort Study
Einarson A, Choi J, Koren G. The Hospital for Sick Children, The Motherisk Program, Toronto, ON, Canada.
1:45 PM–2:00 PM 30 Antiepileptic Drugs as Cognitive Teratogens: A Prospective Study of Creativity in Children Exposed to Valproate, Carbamazepine, and Lamotrigine Monotherapy
McVearry KM1, Meador K2. 1Georgetown University Department of Neurology, Washington, DC, United States, 2University of Florida McKnight Brain Institute, Gainesville, FL, United States.
2:00 PM–2:15 PM 31 Intrauterine Growth During Different Time Windows in Relation to Mental Development at 13 Months Postpartum
von Ehrenstein OS, Mikolajczyk RT, Zhang J. National Institute of Child Health & Human Development / NIH, Bethesda, MD, United States.
2:15 PM–2:30 PM 32 Low-Level Prenatal Exposure to Tobacco Smoke and Newborn Neurobehavior
Yolton K1, Khoury J1, Lanphear B1, Succop P2, Lester B3. 1Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States, 2University of Cincinnati, Cincinnati, OH, United States, 3Brown University, Providence, RI, United States.
2:30 PM–2:45 PM 33 Binge Ethanol Exposure Over Postnatal days 4-9 and 7-9 Produces Deficits in Trace and Long-Delay Eyeblink Conditioning in the Rat
Murawski N, Burman M, Brown K, Stanton M. University of Delaware, Newark, DE, United States.
2:45 PM–3:00 PM 34 Prenatal Exposure to Cocaine Alters Neurobehavioral Developmental Milestones in Rats
Handu SS1,2, Datta H2, Sankaranarayanan A2, James H1, Al Khaja KAJ1, Sequeira RP1. 1Department of Pharmacology & Therapeutics, College of Medicine & Medical Sciences, Arabian Gulf University, Manama, Bahrain, 2Department of Pharmacology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
3:00 PM–3:15 PM 35 Intravenous Cocaine Administration Throughout Pregnancy in the Rat: Preliminary Results
Dow-Edwards D, Zhao N, Jozwicka A. State University of New York, Brooklyn, NY, United States.
1:30 PM–4:30 PM EMBRYONIC STEM CELLS AND BEYOND SYMPOSIUM—Regency Main Ballroom
Organized by Janet Uriu-Adams, University of California, Davis and Christina D. Chambers, University of California, San Diego
Chairpersons: Rocky S. Tuan, National Institute of Arthritis, NIH and Gary Schoenwolf,University of Utah
1:30 PM–1:45 PM Introduction
Speaker: Rocky S. Tuan, National Institute of Arthritis, NIH
Session I
Moderator: Rocky S. Tuan, National Institute of Arthritis, NIH
1:45 PM–2:15 PM S26 Human Embryonic Stem Cells and the Control of Growth and Differentiation of Human Pluripotent Stem Cells
Speaker: Martin Pera, University of Southern California
2:15 PM–2:45 PM S27 Human Embryonic Stem Cells: Advancing Technology for Therapeutic Application
Speaker: Jane Lebkowski, Geron Corporation
2:45 PM–3:15 PM S28 The Homeostatic Pressure Exerted by Stem Cells in Degenerative or Injured CNS Environments
Speaker: Evan Snyder, Burnham Institute for Medical Research
3:15 PM–3:30 PM Break
Session II
Moderator: Gary Schoenwolf, University of Utah
3:30 PM–4:00 PM S29 Reprogramming Cells to Pluripotency by Defined Factors
Speaker: Nimet Maherali, Harvard University
4:00 PM–4:30 PM S30 Early Developmental Events and Modeling Them In Vitro
Speaker: Mahendra S. Rao, Invitrogen
1:30 PM–5:30 PM TS, OTIS AND INTERNATIONAL SOCIETY FOR PHARMACOEPIDEMIOLOGY (ISPE) JOINT
WORKSHOP—Windjammer Room
Pregnancy Registry Methods
Organized by Lewis B. Holmes, Mass General Hospital for Children
Chairpersons: Allen A. Mitchell, Boston University and Janine E. Polifka, University of Washington
1:30 PM–1:40 PM Introduction
Speaker: Lewis B. Holmes, Mass General Hospital for Children
Session I
Moderator: Allen Mitchell, Slone Epidemiology Center at Boston University
1:40 PM–2:10 PM W1 Informed Consent Processes in Pregnancy Registries
Speaker: Kristine Shields, Merck & Company, Inc.
2:10 PM–2:40 PM W2 Selection of Comparison Groups for Pregnancy Registries
Speaker: Angela Scheuerle, Tesserae Genetics
2:40 PM–3:10 PM W3 Global Marketing of Registries: To the Public and to the Patient
Speaker: Diego F. Wysynski, Amgen Inc.
3:10 PM–3:40 PM Poster Session with Refreshments
(WP1–WP4)
Session II
Moderator: Janine E. Polifka, University of Washington
3:40 PM–4:10 PM W4 Pregnancy Registries: The Importance of Inclusion and Exclusion Criteria
Speaker: Lewis B. Holmes, Mass General Hospital for Children
4:10 PM–4:40 PM W5 Signal Detection and Follow-Up
Speaker: Allen Mitchell, Slone Epidemiology Center at Boston University
4:40 PM–5:00 PM W6 European Perspective: Harmonization of Guidelines for Pregnancy Registries
Speaker: Elisabeth Elefant, Paris TIS
5:00 PM–5:20 PM W7 U.S. FDA Perspective on Pregnancy Registry Data: What Do We Want in the Label
Speaker: Karen B. Feibus, U.S. FDA/CDER/Office of New Drugs
5:20 PM–5:30 PM Conclusion and Topic Suggestions for Next Year
Speaker: Lewis B. Holmes, Mass General Hospital for Children
4:30 PM–5:30 PM NATIONAL CHILDREN’S STUDY UPDATE—Regency Main Ballroom
4:30 PM–5:00 PM National Update: 2008 and Beyond
Speaker: Peter Scheidt, Director National Children’s Study
5:00 PM–5:30 PM NCS in California
Speaker: James Swanson, Child Development Center, University of California, Irvine; Principal Investigator, NCS Orange County Vanguard Center
5:30 PM–7:00 PM SPECAIL SESSION: OPEN DEBATE—Regency 1
One-Generation versus Multi-Generation Reproductive Toxicity Testing
Chairpersons: Donald G. Stump, WIL Research Laboratories and M. Sue Marty, The Dow Chemical Company
5:30 PM–5:45 PM E1 Moving Towards a One-Generation Protocol
Speaker: Susan Makris, U.S. Environmental Protection Agency
5:45 PM–6:00 PM E2 Keeping a Multi-Generation Protocol
Speaker: Paul M.D. Foster, National Institute of Environmental Health Sciences
6:00 PM–7:00 PM Open Discussion
5:30 PM–7:30 PM SPECIAL SESSION—Regency Main Ballroom
Teaching Embryology/Teratology in the 21st Century
Organized by the Student Affairs Committee: Mary Alice Smith, Chairperson
Chairpersons: Mark Torchia, St. Boniface General Hospital and Maia L. Green, University of Louisville
5:30 PM–5:35 PM Introduction: Is Embryology Disappearing from the Curriculum?
Speakers: Mark Torchia, St. Boniface General Hospital and Maia L. Green, University of Louisville
5:35 PM–6:00 PM E3 Evo Devo: Integrating Development and Evolution
Speaker: Scott F. Gilbert, Swarthmore College
6:00 PM–6:25 PM E4 Why Would Anyone Want to Learn Embryology and How Would It be Taught if They Did
Speaker: Thomas W. Sadler
6:25 PM–6:50 PM E5 Teaching Embryology as an Integrated Discipline
Speaker: Thomas E. Kwasigroch, East Tennessee State University
6:50 PM–7:15 PM E6 Using Web-Based Tools for Teaching Embryology
Speaker: Thomas B. Knudsen, National Center for Computational Toxicology
7:15 PM–7:30 PM Open Discussion
Rev. Friday, September 27, 2019; at 10:15:32 AM EST
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