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7:00 AM–8:00 AM ANNUAL MEETING WORKING GROUP MEETING—Spyglass 2
7:00 AM–8:00 AM PUBLICATIONS COMMITTEE MEETING—Cypress 1
7:30 AM–6:00 PM REGISTRATION—Regency Foyer
7:30 AM–8:00 AM COFFEE AND CONTINENTAL BREAKFAST—Monterey Grand
Ballroom
8:00 AM–8:30 AM SPECIAL LECTURE—Regency Main Ballroom
Human Teratogens: Year in Review (L1)
Speaker: Lewis B. Holmes, Mass General Hospital for Children
8:30 AM–11:30 AM TS/NBTS JOINT SYMPOSIUM—Regency Main Ballroom
Pesticides and Neurodevelopment
Chairpersons: Mary E. Gilbert. U.S. Environmental Protection Agency and Susan L. Schantz, University of Illinois
8:30 AM–8:45 AM S7 An Overview of the Centers for Children’s Environmental Health and Disease Prevention: Research, Translation and Outreach
Speaker: Susan L. Schantz, University of Illinois
8:45 AM–9:25 AM S8 Neurodevelopmental Effects of Prenatal Exposure to Chlorpyrifos in an Urban Cohort
Speaker: Virginia Rauh, Columbia University
9:25 AM–10:00 AM S9 Organophosphate Exposure and Neurodevelopment in a Mexican American Farmworker Population: the CHAMACOS Study
Speaker: Brenda Eskenazi, University of California, Berkeley
10:00 AM–10:15 AM Break
10:15 AM–10:50 AM S10 In Utero Exposure to Pesticides and Child Neurodevelopment in a New York City Cohort
Speaker: Mary Wolff, Mt. Sinai
10:50 AM–11:30 AM S11 Pesticide Exposure in Children: Evidence for a Take Home Pathway
Speaker: Elaine M. Faustman, University of Washington
8:30 AM–11:30 AM PLATFORM SESSION II—Regency 4
Diabetes in Pregnancy: Mechanisms and Outcomes
Chairpersons: James L. Mills, National Institute of Child Health and Human Development and Barbara F. Hales, McGill University
8:30 AM–8:45 AM 10 Tibial Hemimelia with Preaxial Hallucal Polydactyly in Infants of Diabetic Mothers
Adam MP1, Hudgins L2, Carey JC3, Hall BD4, Coleman K1, Perez-Aytes A5, Graham, Jr. JM6. 1Emory University, Atlanta, GA, United States, 2Stanford Medical Center, Palo Alto, CA, United States, 3University of Utah Medical Center, Salt Lake City, UT, United States, 4University of Kentucky Medical Center, Lexington, KY, United States, 5Hospital Universitario Infantil La Fe, Valentia, Spain, 6Cedars-Sinai Medical Center, Los Angeles, CA, United States.
8:45 AM–9:00 AM 11 Does Periconceptional Use of Vitamin Supplements Containing Folic Acid Attenuate the Risk for Diabetes-Associated Birth Defects?
Correa A1, Gilboa SM1, Botto LD2, Moore CA1, Hobbs CA3, Cleves M3, Colarusso T1, Waller DK4, Reece EA5. 1CDC, NCBDDD, Atlanta, GA, United States, 2University of Utah, Salt Lake City, UT, United States, 3University of Arkansas, Little Rock, AR, United States, 4University of Texas, Houston, TX, United States, 5University of Maryland, Baltimore, MD, United States.
9:00 AM–9:15 AM 12 The Interrelation of Hyperglycemia, Hypoxia and oxidative Stress in Diabetes-Induced Embryopathy in Rats
Ornoy A, Bishitz N, Rand S. Hebrew University Hadassah Medical School, Jerusalem, Israel.
9:15 AM–9:30 AM 13 Apoptosis Signal-Regulating Kinase 1 (ASK1) Involves in Maternal Diabetes-Induced Neural Tube Defects (NTDS)
Yang P, Zhao Z, Reece EA. Department of Obstetrics, Gynecology & Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, United States.
9:30 AM–9:45 AM 14 Epidemiological Study of Risk Factors for VATER Association: Data from the National Birth Defects Prevention Study 1997–2003
Smelser DT1, Moore CA1, Olney RS1, Crider KS1, Reefhuis J1, Botto LD2, Druschel CM3, Romitti PA4. 11Centers for Disease Control and Prevention, Atlanta, GA, United States, 2University of Utah, Salt Lake City, UT, United States, 3New York State Department of Health, Troy, NY, United States, 4University of Iowa, Iowa City, IA, United States.
9:45 AM–10:00 AM 15 Birth Defect Risk in Diabetic Pregnancy: Implications of Altered Gene Expression in Embryo and Placenta
Kappen C1, Kruger C1, Pavlinkova G2, Salbaum JM1. 1Pennington Biomedical Research Center/LSU, Baton Rouge, LA, United States, 2University of Nebraska Medical Center, Omaha, NE, United States.
10:00 AM–10:15 AM Break
Gene Expression and Genomics
Chairpersons: Diana M. Jariloff, University of British Columbia and Michael F. O’Hara, Novartis Pharmaceuticals
10:15 AM–10:30 AM 16 Gene Expression Profile Induced by Testosterone in the Fetal Rat Testis
Daston GP, Overmann GJ, Carr GJ, Tiesman JP, Naciff JM. Procter & Gamble, Cincinnati, OH, United States.
10:30 AM–10:45 AM 17 INSL3 Levels in Amniotic Fluid of Human Fetuses
Ivell RA2, Ivell R2, Driscoll D1, Manson JM1. 1University of Pennsylvania, Philadelphia, PA, United States, 2University of Adelaide, Adelaide, Australia.
10:45 AM–11:00 AM 18 Evaluation of MicroRNAs as Markers of Development Toxicity
Streck RD, Kumpf SW. Developmental & Reproductive Toxicology, Pfizer Global R & D, Groton, CT, United States.
11:00 AM–11:15 AM 19 Regulation of Folate Receptor 1 Expression in the Yolk Sac
Salbaum JM1, Finnell RH2, Kappen C1. 1Pennington Biomedical Research Center, Baton Rouge, LA, United States, 2Texas Institute for Genomic Medicine, Houston, TX, United States.
11:15 AM–11:30 AM 20 An Approach to Using Genomics Data in Risk Assessment: Dibutyl Phthalate (DBP) Case Study
Euling SY1, Makris S1, Sen B2, White L2, Benson R3, Gaido KW4, Kim AS1, Hester S5, Wilson VS5, Keshava C1, Keshava N1, Foster PM6, Androulakis IP7, Ovacik M7, Ierapetritou MG7, Gray, Jr. LE5, Thompson C1, Chiu W1. 1NCEA, US EPA, Washington, DC, United States, 2NCEA, US EPA, Research Triangle Park, NC, United States, 3Region 8, US EPA, Denver, CO, United States, 4The Hamner Institute, Research Triangle Park, NC, United States, 5NHEERL, US EPA, Research Triangle Park, NC, United States, 6NIEHS, Research Triangle Park, NC, United States, 7ebCTC, Rutgers/UMDNJ, Piscataway, NJ, United States.
11:30 AM–1:00 PM LUNCH ON OWN
11:30 AM–1:00 PM PAST PRESIDENT’S LUNCHEON (By invitation only)—Windjammer 1
11:30 AM–12:30 PM STUDENT AFFAIRS COMMITTEE MEETING—Spyglass 2
1:00 PM–2:00 PM ROBERT L. BRENT LECTURE—Regency Main Ballroom
Can Maternal Hypertension Be Safely Treated During Pregnancy?
Speaker: Jan M. Friedman, University of British Columbia
2:00 PM–4:30 PM NUTRITION AND FOOD SAFETY PRE-CONCEPTION TO ADOLESCENCE SYMPOSIUM—Regency Main Ballroom
Chairpersons: Carl L. Keen, University of California, Davis and William Slikker, Jr., National Center for Toxicological Research
2:00 PM–2:10 PM Introduction
Speaker: William Slikker, Jr., National Center for Toxicological Research
2:10 PM–2:45 PM S12 Changing Expectations of Food and Food Safety
Speaker: Carl Keen, University of California, Davis
2:45 PM–3:15 PM S13 Flavonoids and Infant Leukemia
Speaker: Logan G. Spector, University of Minnesota Medical School
3:15 PM–3:30 PM Break
3:30 PM–4:00 PM S14 Acrylamide in Food and Issues of Safety During Development
Speaker: Merle Paule, National Center for Toxicological Research
4:00 PM–4:30 PM S15 Concepts and Challenges in Developing Personalized Nutrition and Medicine for Pregnant Women and Infants
Speaker: Jim Kaput, University of California, Davis
2:00 PM–4:30 PM JOINT TS/OTIS PLATFORM SESSION II—Regency 1
Chronic Maternal Diseases and Effects of Their Treatment
Chairpersons: Jan M. Friedman, University of British Columbia and Diana Johnson, University of California, San Diego
2:00 PM–2:05 PM Introduction
2:05 PM–2:20 PM 21 Mycophenolate Mofetil Embryopathy: A Recognizable Phenotype
Anderka MT1, Lin AE2, 1, Abuelo D3,4, Mitchell AA5. 1Massachusetts Department of Public Health, Boston, MA, United States, 2Massachusetts General Hospital, Boston, MA, United States, 3Rhode Island Hospital, Providence, RI, United States, 4Hasbro Children’s Hospital, Providence, RI, United States, 5Slone Epidemiology Center at Boston University, Boston, MA, United States.
2:20 PM–2:40 PM 22 Pregnancy Outcome and Cognitive Development of Children Exposed In Utero to Cyclosporine Following Maternal Renal Transplant
Nulman I1,2, Sgro M1,2, Barrera M1,2, Chitayat D1,2, Cairney J3,1, Koren G1,2. 1The Hospital For Sick Children, Toronto, ON, Canada, 2University of Toronto, Toronto, ON, Canada, 3Centre for Addiction and Mental Health, Toronto, ON, Canada.
2:40 PM–3:00 PM 23 Multiple Sclerosis—Effects of Immunomodulatory Therapy on Pregnancy Outcome: An Observational Study of the Teratology Information Service Berlin, Germany
Weber-Schoendorfer C. Pharmokovigilanz- und Beratungszentrum, Embryonaltoxikologie, Berlin, Germany.
3:00 PM–3:15 PM 24 Asthma Exacerbations During Pregnancy: The Role of Fetal Sex
Bakhireva LN1, Tucker CM2, Schatz M3, Jones KL4, Slymen DJ5, Klonoff-Cohen HS4, Gresham L5, Johnson D4, Chambers CD4. OTIS Collaborative Research Group6. 1University of New Mexico, Albuquerque, NM, United States, 2Midwestern University, Glendale, AZ, United States, 3Kaiser-Permanente Medical Center, San Diego, CA, United States, 4University of California, San Diego, La Jolla, CA, United States, 5San Diego State University, San Diego, CA, United States, 6OTIS, San Diego, CA, United States.
3:15 PM–3:30 PM Break
Molecular and Environmental Pathways Leading to Birth Defects
Chairpersons: Andrew F. Olshan, University of North Carolina and
Elizabeth A. Conover, University of Nebraska
3:30 PM–3:45 PM 25 Maternal Nutrient Intake and Risk for Transverse and Longitudinal Limb Deficiency: Results from the National Birth Defects Prevention Study, 1997–2003
Robitaille J1, Carmichael SL2, Shaw GM2, Olney RS1. 1CDC, NCBDDD, Atlanta, GA, United States, 2March of Dimes Birth Defects Foundation, California Birth Defects Monitoring Program, Berkeley, CA, United States.
3:45 PM–4:00 PM 26 Maternal Caffeine Intake During Pregnancy and Risk of Orofacial Clefts
Collier SA1, Browne ML2, Rasmussen SA1, Honein MA1. 1National Center on Birth Defects and Developmental Disabilities, Atlanta, GA, United States, 2Bureau of Environmental & Occupational Epidemiology, New York State Department of Health, Troy, NY, United States.
4:00 PM–4:15 PM 27 A Role for DNA Methylation in the Causation of Cleft Lip and Palate in the A/WYSN Mouse Model
Juriloff DM1, Harris MJ1, Gagnier L2, Mager DL1,2. 1Dept Medical Genetics, University of British Columbia, Vancouver, BC, Canada, 2Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada.
4:15 PM–4:30 PM 28 Hypospadias and Maternal Intake of Nutrients Related to Methylation
Carmichael SL, Yang W, Correa A, Olney RS, Shaw GM. March of Dimes, California Research Division, Oakland, CA, United States.
4:30 PM–5:30 PM STRATEGIC PLANNING SESSION UPDATE—Regency Main Ballroom
5:30 PM–7:30 PM TS/NBTS/OTIS JOINT POSTER SESSION AND EXHIBITS OPEN —Monterey Grand Ballroom
Society for Birth Defects Research and Prevention Posters: P1–P44
NBTS Posters: NBTS 17–NBTS 25
OTIS Posters: OTIS P1–OTIS P9
7:30 PM–9:30 PM MARTA/MTA Student CAREER EVENT—Cypress 1
Rev. Friday, September 27, 2019; at 11:15:32 AM EST
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